Effect of resin infiltration and self-assembling peptide P11-4 on shear bond strength of conventional metal brackets: A comparative in vitro study

Description :

White spot lesions (WSLs) represent early enamel lesions and are frequently present in patients seeking orthodontic treatment. Conventional preventive strategies, such as fluoride toothpaste and varnish tend to reduce risk of new WSLs but has limitations regarding their remineralization. This study aims to evaluate the effect of two remineralizing agents on the shear bond strength when applied before bonding to artificially induced WSLs. Resin infiltration (ICON®) tends to occlude the lesion with lower-viscosity resin, while self-assembling peptide P11-4 (CurodontTM) tends to diffuse into the lesion, nucleates hydroxyapatite, and remineralizes it. Recent studies mainly evaluate these techniques for their prevention and post-orthodontic management of WSLs and not their effect on SBS of WSLs. Three groups will be evaluated and compared; a control group (untreated WSLs), a group treated with resin infiltration (ICON®), and a group treated with self-assembling peptide P11-4 (CurodontTM Repair). This approach creates artificial WSLs, applies each remineralization protocol, bonds metallic brackets, and tests SBS using universal testing machine.

Titulaire :
AKL Roula

Contact USJ :
roula.akl@usj.edu.lb

Chercheur(s) :
Dr Roula AKL

Projet présenté au CR, le : 02/01/2026

Projet achevé auprès du CR : 02/04/2026